Quantification of adenovirus DNA in plasma for management of infection in stem cell graft recipients

被引：71

作者：

Lankester, AC

van Tol, MJD

Claas, ECJ

Vossen, JM

Kroes, ACM

机构：

[1] Leiden Univ, Med Ctr, Dept Pediat, NL-2300 RC Leiden, Netherlands

[2] Leiden Univ, Med Ctr, Dept Med Microbiol, NL-2300 RC Leiden, Netherlands

来源：

CLINICAL INFECTIOUS DISEASES | 2002年 / 34卷 / 06期

关键词：

D O I：

10.1086/339073

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We used a real-time polymerase chain reaction method for quantification of adenovirus to monitor the dynamics of viral DNA load in plasma in pediatric stem-cell graft recipients. Two cases are described to demonstrate that detection and quantification of the adenovirus DNA load at regular intervals may be important to document the stage of adenovirus infection, to make decisions on clinical intervention, and to accurately monitor the response to antiviral therapy.

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收藏

页码：864 / 867

页数：4

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