Use of electrospinning technique for biomedical applications

被引:1460
作者
Agarwal, Seema [1 ]
Wendorff, Joachim H.
Greiner, Andreas
机构
[1] Univ Marburg, Dept Chem, D-35032 Marburg, Germany
关键词
Electrospinning; Biomedical applications; Tissue engineering; Wound dressing; Drug release;
D O I
10.1016/j.polymer.2008.09.014
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The electrospinning technique provides non-wovens to the order of few nanometers with large surface areas, ease of functionalisation for various purposes and superior mechanical properties. Also, the possibility of large scale productions combined with the simplicity of the process makes this technique very attractive for many different applications. Biomedical field is one of the important application areas among others utilising the technique of electrospinning like filtration and protective material, electrical and optical applications, sensors, nanofiber reinforced composites etc. Electrospinning assembly can be modified in different ways for combining materials properties with different morphological structures for these applications. The importance of electrospinning, in general, for biomedical applications like tissue engineering drug release, wound dressing, enzyme immobilization etc. is highlighted in this feature article. The focus is also on the types of materials that have been electrospun and the modifications that have been carried Out in conventional electrospinning apparatus keeping in view the specific needs for various biomedical applications. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5603 / 5621
页数:19
相关论文
共 132 条
  • [1] Biodegradable nanomats produced by electrospinning: Expanding multifunctionality and potential for tissue engineering
    Ashammakhi, N.
    Ndreu, A.
    Piras, A. M.
    Nikkola, L.
    Sindelar, T.
    Ylikauppila, H.
    Harlin, A.
    Gomes, M. E.
    Neves, N. M.
    Chiellini, E.
    Chiellini, F.
    Hasirci, V.
    Redl, H.
    Reis, R. L.
    [J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2007, 7 (03) : 862 - 882
  • [2] Incremental changes in anisotropy induce incremental changes in the material properties of electrospun scaffolds
    Ayres, Chantal E.
    Bowlin, Gary L.
    Pizinger, Ryan
    Taylor, Leander T.
    Keen, Christopher A.
    Simpson, David G.
    [J]. ACTA BIOMATERIALIA, 2007, 3 (05) : 651 - 661
  • [3] Barnes CP, 2006, J ENG FIBER FABR, V1, P16
  • [4] Alginate-based nanofibrous scaffolds: Structural, mechanical, and biological properties
    Bhattarai, Narayan
    Li, Zhensheng
    Edmondson, Dennis
    Zhang, Miqin
    [J]. ADVANCED MATERIALS, 2006, 18 (11) : 1463 - +
  • [5] Controlled synthesis and structural stability of alginate-based nanofibers
    Bhattarai, Narayan
    Zhang, Miqin
    [J]. NANOTECHNOLOGY, 2007, 18 (45)
  • [6] Poly(l-lactide-co-glycolide) biodegradable microfibers and electrospun nanofibers for nerve tissue engineering: an in vitro study
    Bini, T. B.
    Gao, Shujun
    Wang, Shu
    Ramakrishna, S.
    [J]. JOURNAL OF MATERIALS SCIENCE, 2006, 41 (19) : 6453 - 6459
  • [7] Electrospun poly-l-lacticle nanofibres as scaffolds for tissue engineering
    Boudriot, U
    Dersch, R
    Goetz, B
    Griss, P
    Greiner, A
    Wendorff, JH
    [J]. BIOMEDIZINISCHE TECHNIK, 2004, 49 (09): : 242 - 247
  • [8] Electrospinning approaches toward scaffold engineering - A brief overview
    Boudriot, Ulrich
    Dersch, Roland
    Greiner, Andreas
    Wendorff, Joachim H.
    [J]. ARTIFICIAL ORGANS, 2006, 30 (10) : 785 - 792
  • [9] Nanofibrous materials and their applications
    Burger, Christian
    Hsiao, Benjamin S.
    Chu, Benjamin
    [J]. ANNUAL REVIEW OF MATERIALS RESEARCH, 2006, 36 : 333 - 368
  • [10] Electrospun polyphosphazene nanofibers for in vitro rat endothelial cells proliferation
    Carampin, Paolo
    Conconi, Maria Teresa
    Lora, Silvano
    Menti, Anna Michela
    Baiguera, Silvia
    Bellini, Silvia
    Grandi, Claudio
    Parnigotto, Pier Paolo
    [J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2007, 80A (03) : 661 - 668