Natural iron isotope variations in human blood

被引：172

作者：

Walczyk, T

von Blanckenburg, F

机构：

[1] Swiss Fed Inst Technol, Inst Food Sci, Human Nutr Lab, CH-8803 Ruschlikon, Switzerland

[2] Univ Bern, CH-3012 Bern, Switzerland

来源：

SCIENCE | 2002年 / 295卷 / 5562期

关键词：

D O I：

10.1126/science.1069389

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Isotopic analysis of human blood and liver and muscle tissue indicates that each individual bears a long-term iron (Fe) isotope signature in the blood. Blood and tissue differ slightly in isotopic composition and are depleted by up to 2.6 per mil in Fe-56 relative to Fe-54 when compared to dietary Fe. The Fe-56/Fe-54 isotope ratio in the blood of mates is, on average, lower by 0.3 per mil than that of females. These results suggest that Fe isotope effects in the blood reflect differences in intestinal Fe absorption between individuals and genotypes.

引用

页码：2065 / 2066

页数：2

共 17 条

[1] Nonbiological fractionation of iron isotopes [J].