One-pot synthesis of 3-alkyl-2,4-dinitrocyclohexanols, under solventless conditions using basic alumina

被引：22

作者：

Ballini, R ^{[1
]}

Barboni, L ^{[1
]}

Fiorini, D ^{[1
]}

Giarlo, G ^{[1
]}

Palmieri, A ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

GREEN CHEMISTRY | 2005年 / 7卷 / 12期

关键词：

D O I：

10.1039/b512617g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

3-Alkyl-2,4-dinitrocyclohexanols can be prepared in a one-pot procedure by reaction of 1,3-dinitroalkanes with acrolein, catalysed by basic alumina and in the absence of any solvent. The synthesis proceeds using tandem Michael/nitroaldol (Henry) reactions and allows satisfactory to good yields of the title compounds. Moreover, several functionalities can be preserved under our conditions.

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页码：828 / 829

页数：2

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