Development of therapeutics: opportunities within complementary and alternative medicine

被引：59

作者：

Engel, LW ^{[1
]}

Straus, SE ^{[1
]}

机构：

[1] NIH, NCCAM, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS DRUG DISCOVERY | 2002年 / 1卷 / 03期

关键词：

D O I：

10.1038/nrd750

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Whereas other components of the National Institutes of Health support the discovery and subsequent development of novel chemical entities into drugs, the National Center for Complementary and Alternative Medicine (NCCAM) studies complex natural products that are marketed as dietary supplements. This article contrasts the regulatory framework for dietary supplements and drugs, outlines the challenges of evaluating dietary supplements for safety and clinical effectiveness, and describes the evolving drug model for botanicals.

引用

页码：229 / 237

页数：9

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