Methyl magic and HAT tricks

被引：5

作者：

Dutnall, RN ^{[1
]}

Denu, JM

机构：

[1] Univ Calif San Diego, Div Biol Sci, Mol Biol Sect, La Jolla, CA 92093 USA

[2] Oregon Hlth & Sci Univ, Dept Biochem & Mol Biol, Portland, OR 97201 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2002年 / 9卷 / 12期

关键词：

D O I：

10.1038/nsb1202-888

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structures of four lysine methyltransferases give us the first glimpse of the molecular architecture responsible for histone/protein lysine methylation, whereas a recent study of the Esa1 histone acetyltransferase suggests that lysine acetyltransferases still have surprises in store.

引用

页码：888 / 891

页数：4

共 30 条

[1] Histone methylation: Dynamic or static? [J].

Bannister, AJ ;

Schneider, R ;

Kouzarides, T .

CELL, 2002, 109 (07) :801-806

[2] The active site of the SET domain is constructed on a knot [J].

Jacobs, SA ;

Harp, JM ;

Devarakonda, S ;

Kim, Y ;

Rastinejad, F ;

Khorasanizadeh, S .

NATURE STRUCTURAL BIOLOGY, 2002, 9 (11) :833-838

[3] Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail [J].

Jacobs, SA ;

Khorasanizadeh, S .

SCIENCE, 2002, 295 (5562) :2080-2083

[4] Translating the histone code [J].

Jenuwein, T ;

Allis, CD .

SCIENCE, 2001, 293 (5532) :1074-1080

[5] Re-SET-ting heterochromatin by histone methyltransferases [J].

Jenuwein, T .

TRENDS IN CELL BIOLOGY, 2001, 11 (06) :266-273

[6] Histone methylation in transcriptional control [J].

Kouzarides, T .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2002, 12 (02) :198-209

[7] The many faces of histone lysine methylation [J].

Lachner, M ;

Jenuwein, T .

CURRENT OPINION IN CELL BIOLOGY, 2002, 14 (03) :286-298

[8] REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE - EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE [J].

LEWENDON, A ;

MURRAY, IA ;

SHAW, WV ;

GIBBS, MR ;

LESLIE, AGW .

BIOCHEMISTRY, 1994, 33 (07) :1944-1950

[9] Structure of the SET domain histone lysine methyltransferase Clr4 [J].

Min, JR ;

Zhang, X ;

Cheng, XD ;

Grewal, SIS ;

Xu, RM .

NATURE STRUCTURAL BIOLOGY, 2002, 9 (11) :828-832

[10] Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly [J].

Nakayam, J ;

Rice, JC ;

Strahl, BD ;

Allis, CD ;

Grewal, SIS .

SCIENCE, 2001, 292 (5514) :110-113

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