Vascular endothelium is a site of free radical production and inflammation in areas of neuronal loss in thiamine-deficient brain

被引：36

作者：

Calingasan, NY ^{[1
]}

Gibson, GE ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Burke Med Res Inst, White Plains, NY 10605 USA

来源：

VASCULAR FACTORS IN ALZHEIMER'S DISEASE | 2000年 / 903卷

关键词：

D O I：

10.1111/j.1749-6632.2000.tb06386.x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：353 / 356

页数：4

共 16 条

[1]

BLASS JP, 1991, REV NEUROL, V147, P513

[2]

Bolanos JP, 1997, J NEUROCHEM, V68, P2227

[3]

Calingasan N. Y., 1999, Society for Neuroscience Abstracts, V25, P323

[4] BLOOD-BRAIN-BARRIER ABNORMALITIES IN VULNERABLE BRAIN-REGIONS DURING THIAMINE-DEFICIENCY [J].

CALINGASAN, NY ;

BAKER, H ;

SHEU, KFR ;

GIBSON, GE .

EXPERIMENTAL NEUROLOGY, 1995, 134 (01) :64-72

[5] Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism [J].

Calingasan, NY ;

Park, LCH ;

Calo, LL ;

Trifiletti, RR ;

Gandy, SE ;

Gibson, GE .

AMERICAN JOURNAL OF PATHOLOGY, 1998, 153 (02) :599-610

[6] Oxidative stress is associated with region-specific neuronal death during thiamine deficiency [J].

Calingasan, NY ;

Chun, WJ ;

Park, LCH ;

Uchida, K ;

Gibson, GE .

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1999, 58 (09) :946-958

[7] CORRELATION OF ENZYMATIC, METABOLIC, AND BEHAVIORAL DEFICITS IN THIAMIN DEFICIENCY AND ITS REVERSAL [J].

GIBSON, GE ;

KSIEZAKREDING, H ;

SHEU, KFR ;

MYKYTYN, V ;

BLASS, JP .

NEUROCHEMICAL RESEARCH, 1984, 9 (06) :803-814

[8] EVIDENCE FOR EARLY BLOOD-BRAIN-BARRIER BREAKDOWN IN EXPERIMENTAL THIAMINE-DEFICIENCY IN THE MOUSE [J].

HARATA, N ;

IWASAKI, Y .

METABOLIC BRAIN DISEASE, 1995, 10 (02) :159-174

[9] THIAMINE-DEFICIENCY IN RATS PRODUCES COGNITIVE AND MEMORY DEFICITS ON SPATIAL TASKS THAT CORRELATE WITH TISSUE LOSS IN DIENCEPHALON, CORTEX AND WHITE-MATTER [J].

LANGLAIS, PJ ;

SAVAGE, LM .

BEHAVIOURAL BRAIN RESEARCH, 1995, 68 (01) :75-89

[10] Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia [J].

Park, LCH ;

Zhang, H ;

Sheu, KFR ;

Calingasan, NY ;

Kristal, BS ;

Lindsay, JG ;

Gibson, GE .

JOURNAL OF NEUROCHEMISTRY, 1999, 72 (05) :1948-1958

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