Tagging in combinatorial chemistry: The use of coloured and fluorescent beads

被引：62

作者：

Egner, BJ

Rana, S

Smith, H

Bouloc, N

Frey, JG

Brocklesby, WS

Bradley, M

机构：

[1] UNIV SOUTHAMPTON,DEPT CHEM,SOUTHAMPTON SO17 1BJ,HANTS,ENGLAND

[2] UNIV SOUTHAMPTON,DEPT PHYS,SOUTHAMPTON SO17 1BJ,HANTS,ENGLAND

[3] UNIV SOUTHAMPTON,OPTOELECT RES CTR,SOUTHAMPTON SO17 1BJ,HANTS,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 08期

关键词：

D O I：

10.1039/a608521k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescent confocal microscopy is a practical and very sensitive (fmol bead(-1)) and non-destructive tagging technique for use in combinatorial chemistry.

引用

页码：735 / 736

页数：2

共 8 条

[1] GENERAL-METHOD FOR RAPID SYNTHESIS OF MULTICOMPONENT PEPTIDE MIXTURES
FURKA, A
SEBESTYEN, F
ASGEDOM, M
DIBO, G
[J]. INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1991, 37 (06): : 487 - 493
[2] APPLICATIONS OF COMBINATORIAL TECHNOLOGIES TO DRUG DISCOVERY .1. BACKGROUND AND PEPTIDE COMBINATORIAL LIBRARIES
GALLOP, MA
BARRETT, RW
DOWER, WJ
FODOR, SPA
GORDON, EM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (09) : 1233 - 1251
[3] GENERATION AND USE OF SYNTHETIC PEPTIDE COMBINATORIAL LIBRARIES FOR BASIC RESEARCH AND DRUG DISCOVERY
HOUGHTEN, RA
PINILLA, C
BLONDELLE, SE
APPEL, JR
DOOLEY, CT
CUERVO, JH
[J]. NATURE, 1991, 354 (6348) : 84 - 86
[4] A NEW TYPE OF SYNTHETIC PEPTIDE LIBRARY FOR IDENTIFYING LIGAND-BINDING ACTIVITY
LAM, KS
SALMON, SE
HERSH, EM
HRUBY, VJ
KAZMIERSKI, WM
KNAPP, RJ
[J]. NATURE, 1991, 354 (6348) : 82 - 84
[5] A GENERAL-METHOD FOR MOLECULAR TAGGING OF ENCODED COMBINATORIAL CHEMISTRY LIBRARIES
NESTLER, HP
BARTLETT, PA
STILL, WC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (17) : 4723 - 4724
[6] COMPLEX SYNTHETIC CHEMICAL LIBRARIES INDEXED WITH MOLECULAR TAGS
OHLMEYER, MHJ
SWANSON, RN
DILLARD, LW
READER, JC
ASOULINE, G
KOBAYASHI, R
WIGLER, M
STILL, WC
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (23) : 10922 - 10926
[7] Molecular diversity and libraries of structures: Synthesis and screening
Rinnova, M
Lebl, M
[J]. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1996, 61 (02) : 171 - 231
[8] COMBINATORIAL SYNTHESIS - THE DESIGN OF COMPOUND LIBRARIES AND THEIR APPLICATION TO DRUG DISCOVERY
TERRETT, NK
GARDNER, M
GORDON, DW
KOBYLECKI, RJ
STEELE, J
[J]. TETRAHEDRON, 1995, 51 (30) : 8135 - 8173

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