Microscopic self-organization of enzymic reactions in small volumes

被引：33

作者：

Mikhailov, A

Hess, B

机构：

[1] MAX PLANCK GESELL,FRITZ HABER INST,D-14195 BERLIN,GERMANY

[2] MAX PLANCK INST MED RES,D-69120 HEIDELBERG,GERMANY

来源：

JOURNAL OF PHYSICAL CHEMISTRY | 1996年 / 100卷 / 49期

关键词：

D O I：

10.1021/jp9616627

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Using an enzymic reaction with allosteric product activation as example, we show that allosterically regulated reactions in small volumes may develop strong microscopic correlations between individual molecular reaction events. Such correlations lead to coherent synchronous activity of the enzymic molecular population which is revealed in frequent periodic spiking of the reaction.

引用

页码：19059 / 19065

页数：7

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