Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2

被引：146

作者：

Hiradate, S

Yoshida, S

Sugie, H

Yada, H

Fujii, Y

机构：

[1] Natl Inst Agroenvironm Sci, Dept Biol Safety Sci, Tsukuba, Ibaraki 3058604, Japan

[2] Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan

来源：

PHYTOCHEMISTRY | 2002年 / 61卷 / 06期

关键词：

Bacillus amyloliquefaciens; iturin; cyclic peptide; beta-amino acid; Colletotrichum dematium; mulberry anthracnose;

D O I：

10.1016/S0031-9422(02)00365-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bacillus amyloliquefaciens strain RC-2 produced seven antifungal compounds (1-7) secreted into the culture filtrate. These compounds inhibited the development of mulberry anthracnose caused by the fungus, Colletotrichum dematium. Chemical structural analyses by NMR and FAB-MS revealed that all these compounds were iturins (cyclic peptides with the following sequence: L-Asn --> D-Tyr --> D-Asn --> L-Gln --> L-Pro --> D-Asn --> L-Ser --> D-beta-amino acid -->) and compounds 1-6 are identical to iturins A-2-A-7, respectively. Compound 7 (iturin A-8) is a new iturin, which has a -(CH2)(10)CH(CH3)CH2CH3 group as a side chain in the beta-amino acid in the molecule. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：693 / 698

页数：6

共 18 条

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