Renal genetic disorders related to K+ and Mg2+

被引：13

作者：

Warnock, DG ^{[1
]}

机构：

[1] Univ Alabama Birmingham, Dept Med & Physiol, Div Nephrol, Res & Training Ctr, Birmingham, AL 35294 USA

[2] Univ Alabama Birmingham, Dept Nephrol, Div Nephrol, Res & Training Ctr, Birmingham, AL 35294 USA

来源：

ANNUAL REVIEW OF PHYSIOLOGY | 2002年 / 64卷

关键词：

epithelia transport; epithelial sodium channel; Liddle's syndrome; Bartter's syndrome; Gitelman's syndrome;

D O I：

10.1146/annurev.physiol.64.081501.160000

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The recent knowledge of the renal epithelial transport systems has exploded with the identification, cloning, and characterization of a large number of membrane transport proteins. The fundamental aspects of these transporters are beginning to emerge at the molecular level and are summarized in the accompanying contributions in this volume of the Annual Review of Physiology. The aim of my review is to integrate this body of knowledge with the understanding of the clinical disorders of human mineral homeostasis that accompany gain, loss, or dysregulation of function of these transport systems. The specific focus is on the best defined human clinical syndromes in which there are derangements in K+ and Mg2+ homeostasis.

引用

收藏

页码：845 / 876

页数：32

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