Effect of ibuprofen on bilirubin-albumin binding

被引:63
作者
Ahlfors, CE [1 ]
机构
[1] Calif Pacific Med Ctr, Div Neonatol, San Francisco, CA USA
关键词
D O I
10.1016/j.jpeds.2003.11.027
中图分类号
R72 [儿科学];
学科分类号
100202 [儿科学];
摘要
lbuprofen is used for closing the ductus arteriosus in premature newborn infants. lbuprofen interferes with bilirubin-albumin binding and increases the unbound bilirubin in pooled newborn plasma to levels similar to those produced by sulfisoxazole, a drug that causes kernicterus in premature newborn infants.
引用
收藏
页码:386 / 388
页数:3
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