Some history and use of the random positioning machine, RPM, in gravity related research

被引：246

作者：

van Loon, Jack J. W. A. ^{[1
]}

机构：

[1] ACTA Vrije Univ, Dept Oral Cell Biol, DESC, NL-1081 BT Amsterdam, Netherlands

来源：

ADVANCES IN SPACE RESEARCH | 2007年 / 39卷 / 07期

关键词：

centrifuge; 2D 3D clinostat; random positioning machine; RPM; cell mechanosensing; simulated microgravity; microweight; mechanotransduction;

D O I：

10.1016/j.asr.2007.02.016

中图分类号：

V [航空、航天];

学科分类号：

08 [工学]; 0825 [航空宇航科学与技术];

摘要：

The first experiments using machines and instruments to manipulate gravity and thus learn about its impact to this force onto living systems were performed by Sir Thomas Andrew Knight in 1806, exactly two centuries ago. What have we learned from these experiments and in particular what have we learned about the use of instruments to reveal the impact of gravity and rotation on plants and other living systems? In this essay I want to go into the use of instruments in gravity related research with emphases on the Random Positioning Machine, RPM. Going from water wheel via clinostat to RPM, we will address the usefulness and possible working principles of these hypergravity and mostly called microgravity, or better, micro-weight simulation techniques. (c) 2007 COSPAR. Published by Elsevier Ltd. All rights reserved.

引用

页码：1161 / 1165

页数：5

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