The Influenza Virus Enigma

被引：193

作者：

Salomon, Rachelle ^{[1
]}

Webster, Robert G. ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Infect Dis, Memphis, TN 38105 USA

来源：

CELL | 2009年 / 136卷 / 03期

关键词：

A H5N1 VIRUSES; PANDEMIC INFLUENZA; INTERSPECIES TRANSMISSION; CYTOKINE RESPONSES; HIGH VIRULENCE; PROTECTS MICE; HEMAGGLUTININ; RESISTANT; INFECTION; COMPLEX;

D O I：

10.1016/j.cell.2009.01.029

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia. Here, we discuss the pathogenesis and transmissibility of influenza viruses and we emphasize the need to find better predictors of both seasonal and potentially pandemic influenza.

引用

页码：402 / 410

页数：9

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