Viral arthritis

被引:24
作者
Calabrese, LH
Naides, SJ
机构
[1] Cleveland Clin Fdn, Dept Rheumat & Immunol Dis, Cleveland, OH 44195 USA
[2] Penn State Univ, Milton S Hershey Med Ctr, Dept Med, Div Rheumatol,Arthrit Bone & Joint Ctr, Hershey, PA 17033 USA
[3] Penn State Univ, Milton S Hershey Med Ctr, Dept Microbiol, Div Rheumatol,Arthrit Bone & Joint Ctr, Hershey, PA 17033 USA
[4] Penn State Univ, Milton S Hershey Med Ctr, Dept Immunol, Div Rheumatol,Arthrit Bone & Joint Ctr, Hershey, PA 17033 USA
关键词
D O I
10.1016/j.idc.2005.09.002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The role of viruses in the development of acute and chronic arthritis is complex, because viruses are ubiquitous, and all human beings are occasionally afflicted by viral infections. In general, most viral infections (ie, most respiratory pathogens) are acute and self-limiting and survive by infecting one susceptible host, then moving on to another. Some viruses establish prolonged latency in the host after acute infection, resulting in clinical symptoms after many years of dormancy, such as dermatomal zoster following chicken pox. Still other viral agents produce chronic infections following the primary stage in all (HIV), most (hepatitis C virus), or a minority (hepatitis B virus) of the infected. The mechanisms whereby these infections produce arthritis are diverse and still poorly understood, but are clearly influenced by both host and viral factors. In rubella, viral infection within the joint is probably responsible. For hepatitis B and C, arthritis may result directly from host cellular or humoral immune responses, while other viruses may act indirectly by altering the integrated host defense network, or by inducing frank autoimmunity, as with HIV and HTLV-1. Although viral arthritis is usually self-limited and nondestructive, chronic forms arise in two settings. First, chronic viral arthritis may occur when immunodeficient patients are infected with agents that are short-lived pathogens in normal hosts, leading to chronic or recurrent infection, with arthritis as one sequela. Second, chronic arthritis may also occur with infections that are by their very nature chronic persistent viral illnesses. This review addresses these and other common forms of viral arthritis, such as that caused by parvovirus B19.
引用
收藏
页码:963 / +
页数:19
相关论文
共 89 条
[1]   AN EPIDEMIC OF ROSS RIVER VIRUS-INFECTION IN FIJI, 1979 [J].
AASKOV, JG ;
MATAIKA, JU ;
LAWRENCE, GW ;
RABUKAWAQA, V ;
TUCKER, MM ;
MILES, JAR ;
DALGLISH, DA .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1981, 30 (05) :1053-1059
[2]   EPIDEMIC ERYTHEMA INFECTIOSUM [J].
AGER, EA ;
CHIN, TDY ;
POLAND, JD .
NEW ENGLAND JOURNAL OF MEDICINE, 1966, 275 (24) :1326-&
[3]  
ALTER MJ, 2000, HEPATITIS C, P169
[4]  
AMITAI Y, 1986, HELV PAEDIATR ACTA, V41, P55
[5]   DETECTION OF ANTIBODIES AND ANTIGENS OF HUMAN PARVOVIRUS B19 BY ENZYME-LINKED-IMMUNOSORBENT-ASSAY [J].
ANDERSON, LJ ;
TSOU, C ;
PARKER, RA ;
CHORBA, TL ;
WULFF, H ;
TATTERSALL, P ;
MORTIMER, PP .
JOURNAL OF CLINICAL MICROBIOLOGY, 1986, 24 (04) :522-526
[6]   EXPERIMENTAL PARVOVIRAL INFECTION IN HUMANS [J].
ANDERSON, MJ ;
HIGGINS, PG ;
DAVIS, LR ;
WILLMAN, JS ;
JONES, SE ;
KIDD, IM ;
PATTISON, JR ;
TYRRELL, DAJ .
JOURNAL OF INFECTIOUS DISEASES, 1985, 152 (02) :257-265
[7]  
[Anonymous], ARBOVIRUSES EPIDEMIO
[8]   Safety and immunogenicity of a recombinant parvovirus B19 vaccine formulated with MF59C.1 [J].
Ballou, WR ;
Reed, JL ;
Noble, W ;
Young, NS ;
Koenig, S .
JOURNAL OF INFECTIOUS DISEASES, 2003, 187 (04) :675-678
[9]   NEUROLOGICAL COMPLICATIONS FOLLOWING RUBELLA INFECTION [J].
BECHAR, M ;
DAVIDOVICH, S ;
GOLDHAMMER, G ;
MACHTEY, I ;
GADOTH, N .
JOURNAL OF NEUROLOGY, 1982, 226 (04) :283-287
[10]   HUMAN PARVOVIRUS-B19 INFECTION AMONG HOSPITAL STAFF MEMBERS AFTER CONTACT WITH INFECTED PATIENTS [J].
BELL, LM ;
NAIDES, SJ ;
STOFFMAN, P ;
HODINKA, RL ;
PLOTKIN, SA .
NEW ENGLAND JOURNAL OF MEDICINE, 1989, 321 (08) :485-491