Synthesis of a series of focally-substituted organothiol dendrons

被引：22

作者：

Chen, KY ^{[1
]}

Gorman, CB ^{[1
]}

机构：

[1] N CAROLINA STATE UNIV,DEPT CHEM,RALEIGH,NC 27695

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 26期

关键词：

D O I：

10.1021/jo961527q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of new organothiol-functionalized dendrons of generation 1-4 is described. Several modifications to the original method for preparation of dendrons are detailed that were found to improve the yield and aid in scale-up. A particularly advantageous method for preparation of an aromatic thiol is reported and is employed in this reaction sequence. Several uses of these dendrons are anticipated and briefly described.

引用

页码：9229 / 9235

页数：7

共 37 条

[1] IMPROVEMENTS IN THE SYNTHESIS OF PHENYLACETYLENE MONODENDRONS INCLUDING A SOLID-PHASE CONVERGENT METHOD
BHARATHI, P
PATEL, U
KAWAGUCHI, T
PESAK, DJ
MOORE, JS
[J]. MACROMOLECULES, 1995, 28 (17) : 5955 - 5963
[2] A FACILE SYNTHESIS OF METHANESULFONATE ESTERS
CROSSLAN.RK
SERVIS, KL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (09) : 3195 - &
[3] HALOGENOLYSIS OF METHYL GLYCYRRHETATE WITH LITHIUM IODIDE-DIMETHYLFORMAMIDE
DEAN, PDG
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1965, (NOV): : 6655 - &
[4] STEREOSPECIFIC SYNTHESIS OF SECONDARY-AMINES BY THE MITSUNOBU REACTION
EDWARDS, ML
STEMERICK, DM
MCCARTHY, JR
[J]. TETRAHEDRON LETTERS, 1990, 31 (24) : 3417 - 3420
[5] Greene T. W., 1991, PROTECTIVE GROUPS OR
[6] ONE-STEP SYNTHESIS OF HYPERBRANCHED DENDRITIC POLYESTERS
HAWKER, CJ
LEE, R
FRECHET, JMJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (12) : 4583 - 4588
[7] PREPARATION OF POLYMERS WITH CONTROLLED MOLECULAR ARCHITECTURE - A NEW CONVERGENT APPROACH TO DENDRITIC MACROMOLECULES
HAWKER, CJ
FRECHET, JMJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (21) : 7638 - 7647
[8] MITSUNOBU REACTIONS OF N-ALKYL AND N-ACYL SULFONAMIDES - AN EFFICIENT ROUTE TO PROTECTED AMINES
HENRY, JR
MARCIN, LR
MCINTOSH, MC
SCOLA, PM
HARRIS, GD
WEINREB, SM
[J]. TETRAHEDRON LETTERS, 1989, 30 (42) : 5709 - 5712
[9] SYNTHESIS AND CHARACTERIZATION OF SURFACE-CAPPED, SIZE-QUANTIZED CDS CLUSTERS - CHEMICAL CONTROL OF CLUSTER SIZE
HERRON, N
WANG, Y
ECKERT, H
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (04) : 1322 - 1326
[10] SYNTHETIC METHODS AND REACTIONS .29. CLEAVAGE OF ESTERS AND ETHERS WITH IODOTRIMETHYLSILANE
HO, TL
OLAH, GA
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1976, 15 (12): : 774 - 775

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