Nanomodified surfaces and guidance of nerve cell processes

被引：6

作者：

Johansson, Fredrik ^{[1
]}

Hallstrom, Waldemar ^{[2
]}

Gustavsson, Per ^{[1
]}

Wallman, Lars ^{[3
]}

Prinz, Christelle ^{[2
]}

Montelius, Lars ^{[2
]}

Kanje, Martin ^{[1
]}

机构：

[1] Lund Univ, Dept Cell & Organism Biol, S-22100 Lund, Sweden

[2] Lund Univ, Dept Solid State Phys, S-22100 Lund, Sweden

[3] Lund Univ, Dept Elect Measurements, S-22100 Lund, Sweden

来源：

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B | 2008年 / 26卷 / 06期

关键词：

gallium compounds; III-V semiconductors; nanopatterning; nanowires; polymers; porous materials;

D O I：

10.1116/1.2998698

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 [电气工程]; 0809 [电子科学与技术];

摘要：

Axonal growth and guidance were studied on different micro- and nanostructured surfaces. Nanoimprinted grooves in a polymer, epitaxial III/V nanowires, porous silicon patterns, and chemically altered surfaces were all shown to induce axonal guidance. Neurons were also found to be able to attach and grow on gallium phosphide nanowires without compromising cell survival. The results are important for the construction of a new generation of neuroelectrical interfaces, including high spatial resolution electrodes. The advantages of the different nanostructured surfaces are discussed.

引用

页码：2558 / 2561

页数：4

共 15 条

[1]

Bayliss SC, 1999, ADV MATER, V11, P318, DOI 10.1002/(SICI)1521-4095(199903)11:4<318::AID-ADMA318>3.0.CO

[2]

2-Z

[3]

Curtis A, 1999, BIOCHEM SOC SYMP, V65, P15

[4]

Topographical control of cells [J].