Control of cell migration during Caenorhabditis elegans development

被引:44
作者
Blelloch, R
Newman, C
Kimble, J
机构
[1] Univ Wisconsin, Cell & Mol Biol Program, Madison, WI 53706 USA
[2] Univ Wisconsin, Howard Hughes Med Inst, Madison, WI 53706 USA
[3] Univ Wisconsin, Dept Biochem, Madison, WI 53706 USA
[4] Univ Wisconsin, Dept Med Genet, Madison, WI 53706 USA
[5] Univ Wisconsin, Mol Biol Lab, Madison, WI 53706 USA
关键词
D O I
10.1016/S0955-0674(99)00028-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In Caenorhabditis elegans, cell migration is guided by localized cues, including molecules such as EGL-17/FGF and UNC-6/netrin, These external cues are linked to an intracellular response to migrate, at least in part, by CED-5, a homolog of DOCK180/MBC, and MIG-2, a Rac-like GTPase, In addition, metalloproteases are required for a cell migration that controls organ shape.
引用
收藏
页码:608 / 613
页数:6
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