Prevention versus intervention of type 1 diabetes

被引：9

作者：

Brooks-Worrell, Barbara ^{[1
]}

Palmer, Jerry P.

机构：

[1] Univ Washington, Dept Med, Seattle, WA 98108 USA

来源：

CLINICAL IMMUNOLOGY | 2013年 / 149卷 / 03期

关键词：

Type; 1; diabetes; 2; Islet autoimmunity; Prediction; Intervention; Prevention; STEM-CELL TRANSPLANTATION; DOUBLE-BLIND; DIETARY INTERVENTION; CD3-ANTIBODY THERAPY; NATURAL-HISTORY; INSULIN; ONSET; CHILDREN; RISK; AUTOIMMUNITY;

D O I：

10.1016/j.clim.2013.05.018

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Type 1 diabetes (T1D) is a cell-mediated autoimmune disease. New cases of T1D are on the increase and exogenous insulin therapy is the only intervention regularly initiated for T1D patients. Though tremendous strides have been made in prediction of T1D, prevention and intervention strategies have not experienced the same success. In this review, we will discuss some possible reasons why new intervention therapies for T1D have not been implemented into the mainstream treatment regimen for T1D patients. We will also discuss potential caveats for why prevention and intervention trials in T1D may not have experienced the same success as prediction trials. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：332 / 338

页数：7

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