A novel strategy for the synthesis of oxygenated phenanthrenes involving a combination of Ullmann and McMurry reactions

被引：32

作者：

Gies, AE ^{[1
]}

Pfeffer, M ^{[1
]}

机构：

[1] Univ Strasbourg 1, Lab Synth Metalloinduites, UMR 7513 CNRS, F-67070 Strasbourg, France

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 10期

关键词：

D O I：

10.1021/jo982522r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general synthetic procedure for the preparation of polyoxygenated phenanthrenes from substituted derivatives of benzaldehyde is described. The key compound is a 6,6'-biphenyl-1, 1'-dicarboxaldehyde intermediate formed through an ambient temperature Ullmann coupling. The subsequent McMurry condensation gave rise to the phenanthrene in 45-57% yields.

引用

页码：3650 / 3654

页数：5

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