Oxidative stress mediates apoptosis induced by oxidized low-density lipoprotein and oxidized lipoprotein(a)

被引:31
作者
Heermeier, K
Schneider, R
Heinloth, A
Wanner, C
Dimmeler, S
Galle, J
机构
[1] Univ Hosp Wurzburg, Div Nephrol, Dept Med, D-97080 Wurzburg, Germany
[2] Univ Hosp Frankfurt, Dept Med, Div Cardiol, Frankfurt, Germany
关键词
lipoproteins; cell death; atherogenesis; vascular wall injury; atherosclerosis;
D O I
10.1046/j.1523-1755.1999.00685.x
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
We measured oxidative stress caused by lipoproteins in human umbilical vein endothelial cells and rabbit aorta. Oxidized lipoprotein(a) was the more potent stimulus over oxidized low density lipoprotein, and we believe that both influence the pathogenesis of atherosclerosis.
引用
收藏
页码:1310 / 1312
页数:3
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