Structure of PNA-nucleic acid complexes

被引：6

作者：

Eriksson, M

机构：

[1] IMBG, Biochemistry B, Panum Institute, University of Copenhagen, DK-2200 Copenhagen N

来源：

NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 5-6期

关键词：

D O I：

10.1080/07328319708002925

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solution structure of the PNA-DNA hybrid H-GCTATGTC-NH2.d(GACATAGC), determined by NMR methods, shows a new conformation which has elements of both A- and B-form DNA. Comparison with other PNA-nucleic acid complexes points to common structural features, but also demonstrates the ability of PNA to conform to nucleic acid partners of different conformations.

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页码：617 / 621

页数：5

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