Effects of nortriptyline and paroxetine on postural sway in depressed elderly patients

被引:15
作者
Mamo, DC [1 ]
Pollock, BG [1 ]
Mulsant, B [1 ]
Houck, PR [1 ]
Bensasi, S [1 ]
Miller, MC [1 ]
Redfern, MS [1 ]
Reynolds, CF [1 ]
机构
[1] Univ Pittsburgh, Sch Med, Dept Psychiat, Intervent Res Ctr Late Life Mood Disorders, Pittsburgh, PA 15260 USA
关键词
D O I
10.1176/appi.ajgp.10.2.199
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Tricyclic antidepressants (TCAs) have previously been found to be related to an increased incidence of falls in elderly persons. Recent pharmacoepidemiologic and nursing home studies have suggested that the risk of falls and fractures in elderly patients receiving selective serotonin reuptake inhibitors (SSRIs) is not different from that of patients receiving TCAs. The authors therefore evaluated postural sway in an older population of depressed patients randomly assigned to treatment with either nortriptyline or paroxetine and did not find any change in postural sway after 6 weeks' treatment with either antidepressant. Further studies with other SSRIs are needed.
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页码:199 / 205
页数:7
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