Do the spatial characteristics of myocardial scar tissue determine the risk of ventricular arrhythmias?

被引：27

作者：

Arenal, Angel ^{[1
]}

Hernandez, Jesus

Perez-David, Esther

Rubio-Guivernau, Jose L. ^{[2
,3
]}

Ledesma-Carbayo, Maria J. ^{[2
,3
]}

Fernandez-Aviles, Francisco

机构：

[1] Hosp Gen Univ Gregorio Maranon, Unidad Arritmias, Serv Cardiol, Madrid 28007, Spain

[2] Univ Politecn Madrid, Madrid, Spain

[3] CIBER BBN, Madrid, Spain

来源：

CARDIOVASCULAR RESEARCH | 2012年 / 94卷 / 02期

关键词：

Myocardial scar; Ventricular tachycardia; IMPLANTABLE-CARDIOVERTER-DEFIBRILLATORS; STRUCTURAL HEART-DISEASE; MAGNETIC-RESONANCE; NONISCHEMIC CARDIOMYOPATHY; CARDIAC FIBROBLASTS; DILATED CARDIOMYOPATHY; CONDUCTING CHANNELS; SLOW CONDUCTION; INFARCT SCARS; TACHYCARDIA;

D O I：

10.1093/cvr/cvs113

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Sudden cardiac death is one of the main causes of mortality in patients with structural heart disease. Although an implantable cardioverter defibrillator significantly reduces the mortality rate, many patients never receive a shock. Identification of high-risk patients would reduce the costs associated with this therapy and prevent the deleterious effect of inappropriate discharges. As scar tissue is the substrate of ventricular arrhythmias in patients with structural heart disease, scar characterization could allow stratification of the risk. The objective of this article is to review the role of scar characteristics in the pathogenesis of ventricular arrhythmias in patients with structural heart disease.

引用

页码：324 / 332

页数：9

共 53 条

[1]

Accurate and objective infarct sizing by contrast-enhanced magnetic resonance imaging in a canine myocardial infarction model [J].

Amado, LC ;

Gerber, BL ;

Gupta, SN ;

Szarf, G ;

Schock, R ;

Nasir, K ;

Kraitchman, DL ;

Lima, JAC .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 44 (12) :2383-2389

[2]

Integration of 3D Electroanatomic Maps and Magnetic Resonance Scar Characterization Into the Navigation System to Guide Ventricular Tachycardia Ablation [J].

Andreu, David ;

Berruezo, Antonio ;

Ortiz-Perez, Jose T. ;

Silva, Etelvino ;

Mont, Lluis ;

Borras, Roger ;

Maria de Caralt, Teresa ;

Jesus Perea, Rosario ;

Fernandez-Armenta, Juan ;

Zeljko, Hrvojka ;

Brugada, Josep .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2011, 4 (05) :674-683

[3]

Arenal, A ;

del Castillo, S ;

Gonzalez-Torrecilla, E ;

Atienza, F ;

Ortiz, M ;

Jimenez, J ;

Puchol, A ;

García, J ;

Almendral, J .

CIRCULATION, 2004, 110 (17) :2568-2574

[4]

Ablation of electrograms with an isolated, delayed component as treatment of unmappable monomorphic ventricular tachycardias in patients with structural heart disease [J].

Arenal, A ;

Glez-Torrecilla, E ;

Ortiz, M ;

Villacastín, J ;

Fdez-Portales, J ;

Sousa, E ;

del Castillo, S ;

de Isla, LP ;

Jimenez, J ;

Almendral, J .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2003, 41 (01) :81-92

[5]

Magnetic resonance-based anatomical analysis of scar-related ventricular tachycardia -: Implications for catheter ablation [J].

Ashikaga, Hiroshi ;

Sasano, Tetsuo ;

Dong, Jun ;

Zviman, M. Muz ;

Evers, Robert ;

Hopenfeld, Bruce ;

Castro, Valeria ;

Helm, Robert H. ;

Dickfeld, Timm ;

Nazarian, Saman ;

Donahue, J. Kevin ;

Berger, Ronald D. ;

Calkins, Hugh ;

Abraham, M. Roselle ;

Marbán, Eduardo ;

Lardo, Albert C. ;

McVeigh, Elliot R. ;

Halperin, Henry R. .

CIRCULATION RESEARCH, 2007, 101 (09) :939-947

[6]

Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy [J].

Assomull, Ravi G. ;

Prasad, Sanjay K. ;

Lyne, Jonathan ;

Smith, Gillian ;

Burman, Elizabeth D. ;

Khan, Mohammed ;

Sheppard, Mary N. ;

Poole-Wilson, Philip A. ;

Pennell, Dudley J. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (10) :1977-1985

[7]

Rapid turnover of connexin43 in the adult rat heart [J].

Beardslee, MA ;

Laing, JG ;

Beyer, EC ;

Saffitz, JE .

CIRCULATION RESEARCH, 1998, 83 (06) :629-635

[8]

Infarct morphology identifies patients with substrate for sustained ventricular tachycardia [J].

Bello, D ;

Fieno, DS ;

Kim, RJ ;

Pereles, S ;

Passman, R ;

Song, G ;

Kadish, AH ;

Goldberger, JJ .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (07) :1104-1108

[9]

Evidence that human cardiac myocytes divide after myocardial infarction (Publication with Expression of Concern. See vol. 379, pg. 1870, 2018) [J].

Beltrami, AP ;

Urbanek, K ;

Kajstura, J ;

Yan, SM ;

Finato, N ;

Bussani, R ;

Nadal-Ginard, B ;

Silvestri, F ;

Leri, A ;

Beltrami, CA ;

Anversa, P .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (23) :1750-1757

[10]

Isolated potentials during sinus rhythm and pace-mapping within scars as guides for ablation of post-infarction ventricular tachycardia [J].

Bogun, F ;

Good, E ;

Reich, S ;

Elmouchi, D ;

Igic, P ;

Lemola, K ;

Tschopp, D ;

Jongnarangsin, K ;

Oral, H ;

Chugh, A ;

Pelosi, F ;

Morady, F .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (10) :2013-2019

← 1 2 3 4 5 6 →