Exploring an Anti-Crystal Engineering Approach to the Preparation of Pharmaceutically Active Ionic Liquids

被引：110

作者：

Dean, Pamela M. ^{[1
]}

Turanjanin, Jelena ^{[1
]}

Yoshizawa-Fujita, Masahiro ^{[1
]}

MacFarlane, Douglas R. ^{[1
]}

Scott, Janet L. ^{[1
]}

机构：

[1] Monash Univ, Sch Chem, Clayton, Vic 3800, Australia

来源：

CRYSTAL GROWTH & DESIGN | 2009年 / 9卷 / 02期

关键词：

INTERMOLECULAR INTERACTIONS; SUPRAMOLECULAR SYNTHONS; ACESULFAMATE; PHASES;

D O I：

10.1021/cg8009496

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of salts, some of which are ionic liquids, are prepared from cations and anions drawn from Active Pharmaceutical Ingredients (APIs) and Generally Recognized As Safe (GRAS) materials. Using the solid-state structures of the crystalline salts as a basis, an anti-crystal engineering approach to the preparation of "Active Ionic Liquids" (AILs) is explored.

引用

页码：1137 / 1145

页数：9

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