Kidney and Fabry disease: mechanisms of renal vascular fibrosis

被引：1

作者：

Chatziantoniou, C ^{[1
]}

Dussaule, JC

机构：

[1] Hop Tenon, INSERM, U702, 4 Rue de la Chine, F-75020 Paris, France

[2] Univ Paris 06, Physiol Lab, AP HP, F-75012 Paris, France

来源：

M S-MEDECINE SCIENCES | 2005年 / 21卷

关键词：

D O I：

10.1051/medsci/20052111s20

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

In Fabry disease, the critical step for progression towards renal failure is the appearance of ischemic lesions within renal vesserls. Recent studies in experimental models identified angiotensin II, endothelin and growth factors as key players in the mechanisms of nephroangiosclerosis. In addition, they showed that renal fibrosis is a reversible process providing thus, hope for efficient treatment(s) against chronic renal failure.

引用

页码：20 / 22

页数：3

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