Site-specific effects of mental practice combined with transcranial direct current stimulation on motor learning

被引:57
作者
Foerster, Aguida [1 ]
Rocha, Sergio [1 ]
Wiesiolek, Carine [1 ]
Chagas, Anna Paula [1 ]
Machado, Giselle [1 ]
Silva, Evelyn [1 ]
Fregni, Felipe [2 ]
Monte-Silva, Katia [1 ]
机构
[1] Univ Fed Pernambuco, Dept Phys Therapy, Appl Neurosci Lab, Recife, PE, Brazil
[2] Harvard Univ, Sch Med, Spaulding Rehabil Hosp, Lab Neuromodulat, Boston, MA USA
关键词
brain stimulation; human; motor control; motor imagery; plasticity; IMAGERY; CORTEX; EXCITABILITY; PERFORMANCE; MODULATION; MOVEMENT; STROKE; CEREBELLUM; ACTIVATION; PLASTICITY;
D O I
10.1111/ejn.12079
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Mental practice can induce significant neural plasticity and result in motor performance improvement if associated with motor imagery tasks. Given the effects of transcranial direct current stimulation (tDCS) on neuroplasticity, the current study tested whether tDCS, using different electrode montages, can increase the neuroplastic effects of mental imagery on motor learning. Eighteen healthy right-handed adults underwent a randomised sham-controlled crossover experiment to receive mental training combined with either sham or active anodal tDCS of the right primary motor cortex (M1), right supplementary motor area, right premotor area, right cerebellum or left dorsolateral prefrontal cortex (DLPFC). Motor performance was assessed by a blinded rater using: non-dominant handwriting time and legibility, and mentally trained task at baseline (pre) and immediately after (post) mental practice combined with tDCS. Active tDCS significantly enhances the motor-imagery-induced improvement in motor function as compared with sham tDCS. There was a specific effect for the site of stimulation such that effects were only observed after M1 and DLPFC stimulation during mental practice. These findings provide new insights into motor imagery training and point out that two cortical targets (M1 and DLPFC) are significantly associated with the neuroplastic effects of mental imagery on motor learning. Further studies should explore a similar paradigm in patients with brain lesions.
引用
收藏
页码:786 / 794
页数:9
相关论文
共 88 条
[1]
[Anonymous], 1988, ADV PSYCHOL, DOI DOI 10.1016/S0166-4115(08)60627-5
[2]
Motor imagery of gait: a quantitative approach [J].
Bakker, M. ;
de Lange, F. P. ;
Stevens, J. A. ;
Toni, I. ;
Bloem, B. R. .
EXPERIMENTAL BRAIN RESEARCH, 2007, 179 (03) :497-504
[3]
Imagery effects on the performance of skilled and novice soccer players [J].
Blair, Andrea ;
Hall, Craig ;
Leyshon, Glynn .
JOURNAL OF SPORTS SCIENCES, 1993, 11 (02) :95-101
[4]
Enhancement of non-dominant hand motor function by anodal transcranial direct current stimulation [J].
Boggio, Paulo S. ;
Castro, Leticia O. ;
Savagim, Edna A. ;
Braite, Renata ;
Cruz, Viviane C. ;
Rocha, Renata R. ;
Rigonatti, Sergio P. ;
Silva, Maria T. A. ;
Fregni, Felipe .
NEUROSCIENCE LETTERS, 2006, 404 (1-2) :232-236
[5]
Differential modulatory effects of transcranial direct current stimulation on a facial expression go-no-go task in males and females [J].
Boggio, Paulo Sergio ;
Rocha, Renata Reed ;
da Silva, Mariah Theodoro ;
Fregni, Felipe .
NEUROSCIENCE LETTERS, 2008, 447 (2-3) :101-105
[6]
Bonney M., 1992, AUST OCCUP THER J, V39, P7, DOI [10.1111/j.1440-1630.1992.tb01751.x, DOI 10.1111/J.1440-1630.1992.TB01751.X]
[7]
Single-session tDCS-supported retraining does not improve fine motor control in musician's dystonia [J].
Buttkus, Franziska ;
Baur, Volker ;
Jabusch, Hans-Christian ;
Gomez-Pellin, Maria de la Cruz ;
Paulus, Walter ;
Nitsche, Michael A. ;
Altenmueller, Eckart .
RESTORATIVE NEUROLOGY AND NEUROSCIENCE, 2011, 29 (02) :85-90
[8]
Effects of action observation on physical training after stroke [J].
Celnik, Pablo ;
Webster, Brian ;
Glasser, Davis M. ;
Cohen, Leonardo G. .
STROKE, 2008, 39 (06) :1814-1820
[9]
Gender-specific modulation of short-term neuroplasticity in the visual cortex induced by transcranial direct current stimulation [J].
Chaieb, Leila ;
Antal, Andrea ;
Paulus, Walter .
VISUAL NEUROSCIENCE, 2008, 25 (01) :77-81
[10]
The impact of spatio-temporal constraints on cursive letter handwriting in children [J].
Chartrel, Estelle ;
Vinter, Annie .
LEARNING AND INSTRUCTION, 2008, 18 (06) :537-547