The stable aryl hydrocarbon receptor agonist potency of United Kingdom Continental Shelf (UKCS) offshore produced water effluents

被引：18

作者：

Hurst, MR ^{[1
]}

Chan-Man, YL ^{[1
]}

Balaam, J ^{[1
]}

Thain, JE ^{[1
]}

Thomas, KV ^{[1
]}

机构：

[1] CEFAS, Burnham Lab, Burnham On Crouch CM0 8HA, Essex, England

来源：

MARINE POLLUTION BULLETIN | 2005年 / 50卷 / 12期

关键词：

AhR agonists; offshore platforms; produced water; CALUX monitoring;

D O I：

10.1016/j.marpolbul.2005.07.009

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The in vitro aryl hydrocarbon receptor (AhR) agonist potency of offshore produced water effluents, collected from the United Kingdom Continental Shelf, was determined using the dioxin responsive (DR)-chemically activated luciferase expression (CALUX) assay. Octadecylsilane (C 18) solid phase extraction (SPE) extracts of produced water were exposed to DR-CALUX cells for 24 It in order to investigate the contribution in potency from compounds that are stable to metabolism by the CALUX cells during exposure. The stable AhR agonist potency determined over 24 h was highly variable and ranged from 1 to 430 ng TCDD TEQ(CALUX) 1(-1). These data reflect the highly variable composition of produced water discharges from different production fields. It is recommended that further work be performed to characterise the full range of stable dioxin like AhR agonists present in offshore produced water discharges using techniques such as bioassay-directed analysis. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1694 / 1698

页数：5

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