Fluorescent 2,7-dialkylamino-[1,8]-naphthyridines: Preparation and spectroscopic properties

被引：21

作者：

Hoock, C ^{[1
]}

Reichert, J

Schmidtke, M

机构：

[1] BYK Gulden Lomberg Gmbh, D-78467 Constance, Germany

[2] Univ Jena, Inst Virol, D-07745 Jena, Germany

来源：

MOLECULES | 1999年 / 4卷 / 10期

关键词：

naphthyridines; fluorescence; fluorescent probes;

D O I：

10.3390/41000264

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Substitution of 4-methyl-[1,8]-naphthyridine in 2 and 7 position by alkylamines leads to highly fluorescent compounds. The arrangement of hydrogen donor and acceptor groups of these naphthyridines allows interactions with guanine and guanine cytosine base pairs. The described synthesis offers easy access to these small and stable fluorescent probes.

引用

页码：264 / 271

页数：8

共 22 条

[1] THE USE OF THE FUSED EUTECTIC OF SODIUM AMIDE AND POTASSIUM AMIDE IN ORGANIC SYNTHESES [J].