Antimicrobial properties of highly fluorinated silver(I) tris(pyrazolyl)borates

被引：59

作者：

Dias, HVR

Batdorf, KH

Fianchini, M

Diyabalanage, HVK

Carnahan, S

Mulcahy, R

Rabiee, A

Nelson, K

van Waasbergen, LG

机构：

[1] Univ Texas, Dept Chem & Biochem, Arlington, TX 76019 USA

[2] Univ Texas, Dept Biomed Engn, Arlington, TX 76019 USA

[3] Univ Texas, Dept Biol, Arlington, TX 76019 USA

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 2006年 / 100卷 / 01期

基金：

美国国家科学基金会;

关键词：

silver; antimicrobial; tris(pyrazolyl)borate; Staphylococcus aureus; dimethyl sulfoxide;

D O I：

10.1016/j.jinorgbio.2005.10.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Highly fluorinated tris(pyrazolyl)borate ligand [HB(3,5-(CF3)(2)Pz)(3)](-) has been used in the isolation of air- and light-stable silver complex, [HB(3,5-(CF3)(2)Pz)(3)]Ag(OSMe2). It is a monomeric tetrahedral silver complex with an O-bonded dimethylsulfoxide ligand. The silver adduct [HB(3,5-(CF3)(2)Pz)(3)]Ag(OSMe2) and the related [HB(3,5-(CF3)(2)Pz)(3)] Ag(THF) (where OSMe2 = dimethyl sulfoxide; THF = tetrahydrofuran) show good antibacterial activity, and their antimicrobial efficacy against Staphylococcus aureus is greater than those of AgNO3 and silver sulfadiazine. (C) 2005 Elsevier Inc. All rights reserved.

引用

页码：158 / 160

页数：3

共 37 条

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