Improved large-scale preparation of 4-iodopicolinic acid

被引：8

作者：

Lohse, O

机构：

[1] SANDOZ PHARMA AG, Chem. Proc. R. and D. Department

来源：

SYNTHETIC COMMUNICATIONS | 1996年 / 26卷 / 10期

关键词：

D O I：

10.1080/00397919608003557

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dimethylformamide showed a dramatic catalytic effect in the chlorination of picolinic acid with thionyl chloride. Methyl 4-chloropicolinate was directly transformed to 4-iodopicolinic acid in a good yield.

引用

页码：2017 / 2025

页数：9

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