GRB2: A pivotal protein in signal transduction

[1] HIERARCHY OF BINDING-SITES FOR GRB2 AND SHC ON THE EPIDERMAL GROWTH-FACTOR RECEPTOR [J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (08) : 5192 - 5201

[2] The structural basis of the activation of Ras by Sos [J]. NATURE, 1998, 394 (6691) : 337 - 343

[3] ERKS - A FAMILY OF PROTEIN-SERINE THREONINE KINASES THAT ARE ACTIVATED AND TYROSINE PHOSPHORYLATED IN RESPONSE TO INSULIN AND NGF [J]. CELL, 1991, 65 (04) : 663 - 675

[4] HUMAN SOS1 - A GUANINE-NUCLEOTIDE EXCHANGE FACTOR FOR RAS THAT BINDS TO GRB2 [J]. SCIENCE, 1993, 260 (5112) : 1338 - 1343

[5] SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (11) : 6328 - 6332

[6] Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation [J]. CELL, 1998, 95 (06) : 793 - 803

[7] FUNCTIONAL DIVERGENCE OF THE MAP KINASE PATHWAY - ERK1 AND ERK2 ACTIVATE SPECIFIC TRANSCRIPTION FACTORS [J]. FEBS LETTERS, 1994, 346 (2-3): : 229 - 234

[8] C-ELEGANS CELL-SIGNALING GENE SEM-5 ENCODES A PROTEIN WITH SH2 AND SH3 DOMAINS [J]. NATURE, 1992, 356 (6367) : 340 - 344

[9] THE PRIMARY STRUCTURE OF MEK, A PROTEIN-KINASE THAT PHOSPHORYLATES THE ERK GENE-PRODUCT [J]. SCIENCE, 1992, 258 (5081) : 478 - 480

[10] DALY RJ, 1994, ONCOGENE, V9, P2723

[1] HIERARCHY OF BINDING-SITES FOR GRB2 AND SHC ON THE EPIDERMAL GROWTH-FACTOR RECEPTOR [J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (08) : 5192 - 5201

[2] The structural basis of the activation of Ras by Sos [J]. NATURE, 1998, 394 (6691) : 337 - 343

[3] ERKS - A FAMILY OF PROTEIN-SERINE THREONINE KINASES THAT ARE ACTIVATED AND TYROSINE PHOSPHORYLATED IN RESPONSE TO INSULIN AND NGF [J]. CELL, 1991, 65 (04) : 663 - 675

[4] HUMAN SOS1 - A GUANINE-NUCLEOTIDE EXCHANGE FACTOR FOR RAS THAT BINDS TO GRB2 [J]. SCIENCE, 1993, 260 (5112) : 1338 - 1343

[5] SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (11) : 6328 - 6332

[6] Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation [J]. CELL, 1998, 95 (06) : 793 - 803

[7] FUNCTIONAL DIVERGENCE OF THE MAP KINASE PATHWAY - ERK1 AND ERK2 ACTIVATE SPECIFIC TRANSCRIPTION FACTORS [J]. FEBS LETTERS, 1994, 346 (2-3): : 229 - 234

[8] C-ELEGANS CELL-SIGNALING GENE SEM-5 ENCODES A PROTEIN WITH SH2 AND SH3 DOMAINS [J]. NATURE, 1992, 356 (6367) : 340 - 344

[9] THE PRIMARY STRUCTURE OF MEK, A PROTEIN-KINASE THAT PHOSPHORYLATES THE ERK GENE-PRODUCT [J]. SCIENCE, 1992, 258 (5081) : 478 - 480

[10] DALY RJ, 1994, ONCOGENE, V9, P2723