Lethal African trypanosomiasis in a traveler: MRI and neuropathology

被引：28

作者：

Braakman, HMH

van de Molengraft, FJJM

Hubert, WWA

Boerman, DH

机构：

[1] Rijnstate Hosp, Dept Neurol, NL-6815 AD Arnhem, Netherlands

[2] Rijnstate Hosp, Dept Pathol, Arnhem, Netherlands

来源：

NEUROLOGY | 2006年 / 66卷 / 07期

关键词：

D O I：

10.1212/01.wnl.0000209306.41647.13

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors report a case of human African trypanosomiasis with CNS involvement caused by Trypanosoma brucei rhodesiense in a 52-year-old woman, which relapsed after melarsoprol treatment. After a second regimen, she developed a severe toxic polyneuropathy, progressing to coma and eventually death. MRI revealed rapidly progressive multiple white matter lesions as well as damage of the central gray matter and cortex. The autopsy results confirmed the diagnosis of human African trypanosomiasis.

引用

页码：1094 / 1096

页数：3

共 9 条

[1] HUMAN AFRICAN TRYPANOSOMIASIS (TB GAMBIENSE) - A STUDY OF 16 FATAL CASES OF SLEEPING SICKNESS WITH SOME OBSERVATIONS ON ACUTE REACTIVE ARSENICAL ENCEPHALOPATHY [J].