Antegrade pulsatile arterial-like flow in human limb veins at increased intravascular pressure

被引:5
作者
Kolegard, Roger [1 ]
Eiken, Ola [1 ]
机构
[1] Karolinska Inst, Swedish Def Res Agcy, FOI, S-17177 Stockholm, Sweden
关键词
arteriovenous anastomoses; A-V shunts; transmural pressure; venous flow; venous pulsations; BLOOD-FLOW; VARICOSE-VEINS; SHEAR-STRESS; ARM PAIN; VASODILATATION; DISTENSIBILITY; ENDOTHELIUM;
D O I
10.1111/j.1475-097X.2009.00859.x
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
The purpose was to study the effects of moderately to markedly increased local intravascular pressures on the flow characteristics in human limb veins. The subject was either seated inside a pressure chamber with one arm slipped through a hole in the chamber door (n = 7) or positioned supine with a lower leg extended to the outside (n = 15). By increasing chamber pressure, transmural pressure in the vessels of the test limb was increased up to +150 mmHg for the arm and +240 mmHg for the leg. Venous flow profiles and arterial flow and vessel diameters were measured with ultrasonographic/Doppler techniques. The arm vessels were studied before and during blocking of the blood flow (BBF) through the hand. Antegrade, pulsatile, arterial-like flow were observed at high distending pressures in the brachial and radial veins in all subjects and in similar to 50% of the subjects also in the cephalic vein and posterior tibial veins. In five of seven subjects, blood flow in the brachial vein remained pulsatile even during BBF. That pulsatile flow was observed in all veins may suggest that moderately to markedly elevated intravascular pressures induce propagation of pulse waves from the arteries via the capillaries to the veins, and/or induce considerable arteriovenous shunting, by forcing open arteriovenous anastomoses.
引用
收藏
页码:209 / 215
页数:7
相关论文
共 35 条
[1]   Pulsatile venous Doppler flow lower limbs: Highly indicative of elevated right atrium pressure [J].
AbuYousef, MM ;
Kakish, ME ;
Mufid, M .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1996, 167 (04) :977-980
[2]  
BARCROFT H, 1957, Angeiol Ann Soc Fr Angeiol Histopathol, V9, P24
[3]   PSYCHOPHYSICAL BASES OF PERCEIVED EXERTION [J].
BORG, GAV .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1982, 14 (05) :377-381
[4]  
BURTON AC, 1939, AM J PHYSIOL, V126, P453
[5]   Nutritive and non-nutritive blood flow: rest and exercise [J].
Clark, MG ;
Rattigan, S ;
Clerk, LH ;
Vincent, MA ;
Clark, ADH ;
Youd, JM ;
Newman, JMB .
ACTA PHYSIOLOGICA SCANDINAVICA, 2000, 168 (04) :519-530
[6]   TOTAL AND NUTRITIONAL BLOOD-FLOW IN FINGER [J].
COFFMAN, JD .
CLINICAL SCIENCE, 1972, 42 (03) :243-&
[7]   Comparison of vascular distensibility in the upper and lower extremity [J].
Eiken, O ;
Kölegård, R .
ACTA PHYSIOLOGICA SCANDINAVICA, 2004, 181 (03) :281-287
[8]  
Eiken O, 2001, AVIAT SPACE ENVIR MD, V72, P427
[9]   Pressure-distension relationship in arteries and arterioles in response to 5 wk of horizontal bedrest [J].
Eiken, Ola ;
Kolegard, Roger ;
Mekjavic, Igor B. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2008, 295 (03) :H1296-H1302
[10]   STRUCTURAL FACTOR IN PRIMARY AND SECONDARY HYPERTENSION [J].
FOLKOW, B .
HYPERTENSION, 1990, 16 (01) :89-101