OmniSpect: An Open MATLAB-Based Tool for Visualization and Analysis of Matrix-Assisted Laser Desorption/Ionization and Desorption Electrospray Ionization Mass Spectrometry Images

被引：50

作者：

Parry, R. Mitchell ^{[1
]}

Galhena, Asiri S. ^{[2
]}

Gamage, Chaminda M. ^{[2
]}

Bennett, Rachel V. ^{[2
]}

Wang, May D. ^{[3
,4
]}

Fernandez, Facundo M. ^{[2
]}

机构：

[1] Emory Univ, Wallace H Coulter Dept Biomed Engn, Atlanta, GA 30332 USA

[2] Georgia Inst Technol, Atlanta, GA 30332 USA

[3] Georgia Inst Technol, Wallace H Coulter Dept Biomed Engn, Dept Elect & Comp Engn, Winship Canc Inst,Parker H Petit Inst Bioengn & B, Atlanta, GA 30332 USA

[4] Emory Univ, Atlanta, GA 30332 USA

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2013年 / 24卷 / 04期

基金：

美国国家科学基金会;

关键词：

Mass spectrometry imaging; Desorption electrospray ionization (DESI); Matrix-assisted laser desorption ionization (MALDI); Data processing; Multivariate image analysis; Web-based tool; Software; MATLAB; MULTIVARIATE STATISTICAL-ANALYSIS; TOF-SIMS; CURVE RESOLUTION; SYSTEM;

D O I：

10.1007/s13361-012-0572-y

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We present omniSpect, an open source web-and MATLAB-based software tool for both desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) that performs computationally intensive functions on a remote server. These functions include converting data from a variety of file formats into a common format easily manipulated in MATLAB, transforming time-series mass spectra into mass spectrometry images based on a probe spatial raster path, and multivariate analysis. OmniSpect provides an extensible suite of tools to meet the computational requirements needed for visualizing open and proprietary format MSI data.

引用

页码：646 / 649

页数：4

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