Successful treatment of myelodysplastic syndrome (MDS)-related intestinal Behcet's disease by up-front cord blood transplantation

被引：34

作者：

Nonami, Atsushi ^{[1
]}

Takenaka, Katsuto ^{[1
]}

Sumida, Chinatsu ^{[1
]}

Aizawa, Kumiko ^{[1
]}

Kamezaki, Kenjiro ^{[1
]}

Miyamoto, Toshihiro ^{[1
]}

Harada, Naoki ^{[1
]}

Nagafuji, Koji ^{[1
]}

Teshima, Takanori ^{[1
]}

Harada, Mine ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Med, Dept Internal Med 1, Fukuoka 812, Japan

来源：

INTERNAL MEDICINE | 2007年 / 46卷 / 20期

关键词：

trisomy; 8; cord blood transplantation;

D O I：

10.2169/internalmedicine.46.0291

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Behcet's disease is a chronic, relapsing, inflammatory disease of unknown origin. The association of myelodysplastic syndrome and Behcet's disease is rare, and recent reports have indicated that immunosuppressive agents alone are not sufficient to control Behcet's disease associated with MDS and many patients die of infection or hemorrhage. We report a case of MDS with intestinal Behcet's disease. We performed cord blood transplantation with a myeloablative regimen as the primary treatment. The patient achieved complete remission for both diseases, which continued for more than 16 months. Our experience suggests that CBT may provide a potent therapeutic option for the treatment of MDS-related Behcet's disease.

引用

页码：1753 / 1756

页数：4

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