Design of a High-Throughput Flow Perfusion Bioreactor System for Tissue Engineering

被引：25

作者：

Dahlin, Rebecca L. ^{[1
]}

Meretoja, Ville V. ^{[1
]}

Ni, Mengwei ^{[1
]}

Kasper, F. Kurtis ^{[1
]}

Mikos, Antonios G. ^{[1
]}

机构：

[1] Rice Univ, Dept Bioengn, Houston, TX 77251 USA

来源：

TISSUE ENGINEERING PART C-METHODS | 2012年 / 18卷 / 10期

基金：

美国国家卫生研究院;

关键词：

CULTURE;

D O I：

10.1089/ten.tec.2012.0037

中图分类号：

Q813 [细胞工程];

学科分类号：

100113 [医学细胞生物学];

摘要：

Flow perfusion culture is used in many areas of tissue engineering and offers several key advantages. However, one challenge to these cultures is the relatively low-throughput nature of perfusion bioreactors. Here, a flow perfusion bioreactor with increased throughput was designed and built for tissue engineering. This design uses an integrated medium reservoir and flow chamber in order to increase the throughput, limit the volume of medium required to operate the system, and simplify the assembly and operation.

引用

页码：817 / 820

页数：4

共 13 条

[1]

Abousleiman RI, 2006, ADV EXP MED BIOL, V585, P243

[2]

Design of a flow perfusion bioreactor system for bone tissue-engineering applications [J].