Tissue typing for hematopoietic cell transplantation: Newer techniques and newer antigens for which cross-matching is helpful

被引:1
作者
Iannone, R
Davies, SM
机构
[1] Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
[2] Univ Penn, Philadelphia, PA 19104 USA
[3] Cincinnati Childrens Hosp & Med Ctr, Cincinnati, OH USA
关键词
human leukocyte antigen; tissue typing; natural killer cells; killer immunoglobulin-like receptor; hematopoietic cell transplantation; graft-versus-host disease;
D O I
10.1111/j.1399-3046.2005.00445.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Refinements in human leukocyte antigen (HLA) typing techniques for hematopoietic cell transplantation (HCT) have permitted a more precise assessment of donor-recipient histocompatibility, which has impacted transplantation outcomes. More recently, differences in transplant outcomes associated with killer immunoglobulin-like receptor compatibility have emphasized the potential importance of natural killer (NK) cell typing in HCT. This article reviews the current state of the art for HCT donor selection based on both HLA and NK cell typing.
引用
收藏
页码:76 / 80
页数:5
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