The Wittig reaction with 2-deoxysugars: the role of triphenyl and trialkyltin halides

被引：7

作者：

Costantino, V ^{[1
]}

Imperatore, C ^{[1
]}

Fattorusso, E ^{[1
]}

Mangoni, A ^{[1
]}

机构：

[1] Univ Naples Federico II, Dipartimento Chim Sostanze Nat, I-80131 Naples, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(01)01765-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of the Wittig reaction to prepare chain-extended polyols starting from protected 2-deoxysugars has been investigated. The standard conditions cause alcohol elimination from the deoxysugar, leading to a diene. Triphenyl and tributyltin halides have been found to prevent alcohol elimination, so that the expected alkene is produced. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8185 / 8187

页数：3

共 7 条

[1]

[Anonymous], 1995, MONOSACCHARIDES THEI

[2]

CHAMBERS DB, 1967, J CHEM SOC A, V1, P1759

[3] A mild and easy one-pot procedure for the synthesis of 2-deoxysugars from glycals [J].