Increased CD200 expression in acute myeloid leukemia is linked with an increased frequency of FoxP3+ regulatory T cells

被引:60
作者
Coles, S. J. [1 ]
Hills, R. K. [1 ]
Wang, E. C. Y. [2 ]
Burnett, A. K. [1 ]
Man, S. [2 ]
Darley, R. L. [1 ]
Tonks, A. [1 ]
机构
[1] Cardiff Univ, Inst Canc & Genet, Dept Haematol, Cardiff, Wales
[2] Cardiff Univ, Sch Med, Inst Infect & Immun, Cardiff, Wales
基金
英国医学研究理事会;
关键词
DENDRITIC CELLS; HUMANS;
D O I
10.1038/leu.2012.75
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
引用
收藏
页码:2146 / 2148
页数:4
相关论文
共 17 条
[1]
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell [J].
Bonnet, D ;
Dick, JE .
NATURE MEDICINE, 1997, 3 (07) :730-737
[2]
Expression of CD200 on AML blasts directly suppresses memory T-cell function [J].
Coles, S. J. ;
Hills, R. K. ;
Wang, E. C. Y. ;
Burnett, A. K. ;
Man, S. ;
Darley, R. L. ;
Tonks, A. .
LEUKEMIA, 2012, 26 (09) :2148-2151
[3]
Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells [J].
Curti, Antonio ;
Trabanelli, Sara ;
Onofri, Chiara ;
Aluigi, Michela ;
Salvestrini, Valentina ;
Ocadlikova, Darina ;
Evangelisti, Cecilia ;
Rutella, Sergio ;
De Cristofaro, Raimondo ;
Ottaviani, Emanuela ;
Baccarani, Michele ;
Lemoli, Roberto M. .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 (12) :2022-2030
[4]
Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response [J].
Delluc, Stephanie ;
Hachem, Patricia ;
Rusakiewicz, Sylvie ;
Gaston, Auguste ;
Marchiol-Fournigault, Carmen ;
Tourneur, Lea ;
Babchia, Narjes ;
Fradelizi, Didier ;
Regnault, Armelle ;
Sang, Kim Hanh Le Quan ;
Chiocchia, Gilles ;
Buzyn, Agnes .
CANCER IMMUNOLOGY IMMUNOTHERAPY, 2009, 58 (10) :1669-1677
[5]
Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells [J].
Ersvaer E. ;
Liseth K. ;
Skavland J. ;
Gjertsen B.T. ;
Bruserud Ø. .
BMC Immunology, 11 (1)
[6]
Production of intracellular IL-2, TNF-α, and IFN-γ by T cells in B-CLL [J].
Gallego, A ;
Vargas, JA ;
Castejón, R ;
Citores, MJ ;
Romero, Y ;
Millán, L ;
Durántez, A .
CYTOMETRY PART B-CLINICAL CYTOMETRY, 2003, 56B (01) :23-29
[7]
Gorczynski L, 1999, J IMMUNOL, V162, P774
[8]
Gorczynski RM, 2005, TRANSPLANTATION, V79, P488, DOI 10.1097/01.TP.0000152118.51622.F9
[9]
Mahadevan D, 2012, 52 ASH ANN M EXP 246, V2465
[10]
CD4+CD25+ Regulatory T Cell Depletion Improves the Graft-Versus-Tumor Effect of Donor Lymphocytes After Allogeneic Hematopoietic Stem Cell Transplantation [J].
Maury, Sebastien ;
Lemoine, Francois M. ;
Hicheri, Yosr ;
Rosenzwajg, Michelle ;
Badoual, Cecile ;
Cherai, Mustapha ;
Beaumont, Jean-Louis ;
Azar, Nabih ;
Dhedin, Nathalie ;
Sirvent, Anne ;
Buzyn, Agnes ;
Rubio, Marie-Therese ;
Vigouroux, Stephane ;
Montagne, Olivier ;
Bories, Dominique ;
Roudot-Thoraval, Francoise ;
Vernant, Jean-Paul ;
Cordonnier, Catherine ;
Klatzmann, David ;
Cohen, Jose L. .
SCIENCE TRANSLATIONAL MEDICINE, 2010, 2 (41)