Differentiation of radiation necrosis from tumor progression using proton magnetic resonance spectroscopy

被引：119

作者：

Schlemmer, HP

Bachert, P

Henze, M

Buslei, R

Herfarth, KK

Debus, J

van Kaick, G

机构：

[1] Deutsch Krebsforschungszentrum, Res Program Radiol Diagnost & Therapy, D-6900 Heidelberg, Germany

[2] Univ Heidelberg, Dept Nucl Med, Heidelberg, Germany

[3] Univ Bonn, Med Ctr, Dept Neuropathol, D-5300 Bonn, Germany

[4] Univ Heidelberg, Radiol Clin, Heidelberg, Germany

来源：

NEURORADIOLOGY | 2002年 / 44卷 / 03期

关键词：

brain tumor; magnetic resonance imaging; magnetic resonance spectroscopy; positron emission tomography; radionecrosis;

D O I：

10.1007/s002340100703

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report on a young woman who was treated by stereotactic radiotherapy for recurrence of an initially resected low-grade astrocytoma. MRI follow-up examination 7 months after radiotherapy showed a gadolinium-DTPA-enhancing mass lesion indicative of high-grade tumor progression. This assumption was also supported by positron emission tomography with [2-F-18]fluoro-2-deoxy-D-glucose (FDG-PET). In contrast, proton MR spectroscopy (H-1-MRS) indicated radiation necrosis, which was confirmed histopathologically in surgical specimens. Subsequent follow-up examinations up to 19 months after surgery showed no evidence of tumor recurrence.

引用

页码：216 / 222

页数：7

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