Microwave-assisted efficient synthesis of spiro-fused heterocycles under solvent-free conditions

被引：94

作者：

Shaabani, A ^{[1
]}

Bazgir, A ^{[1
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 12期

关键词：

solvent free; multicomponent; microwave; Biginelli reaction; spiro-fused heterocyclic rings; Meldrum's acid; barbituric acid;

D O I：

10.1016/j.tetlet.2004.01.154

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Spiro-fused heterocycles were synthesized in good to high yields by a pseudo four-component reaction of an aldehyde, urea and a cyclic beta-diester or a beta-diamide such as Meldrum's acid or barbituric acid derivatives using microwave irradiation under solvent-free conditions. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：2575 / 2577

页数：3

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