The effects of local spatial structure on epidemiological invasions

被引:612
作者
Keeling, MJ [1 ]
机构
[1] Univ Cambridge, Dept Zool, Cambridge CB2 3EJ, England
基金
英国惠康基金;
关键词
correlation equations; contact networks; spatial heterogeneity; basic reproductive ratio; final size; invasion;
D O I
10.1098/rspb.1999.0716
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Predicting the likely success of invasions is vitally important in ecology and especially epidemiology. Whether an organism can successfully invade and persist in the short-term is highly dependent on the spatial correlations that develop in the early stages of invasion. By modelling the correlations between individuals, we are able to understand the role of spatial heterogeneity in invasion dynamics without the need for large-scale computer simulations. Here, a natural methodology is developed for modelling the behaviour of individuals in a fixed network. This formulation is applied to the spread of a disease through a structured network to determine invasion thresholds and some statistical properties of a single epidemic.
引用
收藏
页码:859 / 867
页数:9
相关论文
共 27 条