Formulations and use of androgens in women

被引：9

作者：

Chu, MC ^{[1
]}

Lobo, RA ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Obstet & Gynecol, New York, NY 10032 USA

来源：

MAYO CLINIC PROCEEDINGS | 2004年 / 79卷 / 04期

关键词：

D O I：

10.1016/S0025-6196(19)30665-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The physiology of normal androgen production in women has been poorly understood. Defining an androgen insufficiency state in women, in the absence of adrenal suppression and/or bilateral oophorectomy, has been difficult. Nevertheless, beneficial effects of androgen on many organ systems, including bone and the brain, are well documented. This review discusses the definition of androgen insufficiency, anticipated effects of androgen treatment on several factors of health, and treatment options for women with androgen insufficiency.

引用

页码：S3 / S7

页数：5

共 29 条

[1] Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment [J].

Bachmann, G ;

Bancroft, J ;

Braunstein, G ;

Burger, H ;

Davis, S ;

Dennerstein, L ;

Goldstein, I ;

Guay, A ;

Leiblum, S ;

Lobo, R ;

Notelovitz, M ;

Rosen, R ;

Sarrel, P ;

Sherwin, B ;

Simon, J ;

Simpson, E ;

Shifren, J ;

Spark, R ;

Traish, A .

FERTILITY AND STERILITY, 2002, 77 (04) :660-665

[2] The effect of deydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, lipid parameters, and health-related quality of life [J].

Barnhart, KT ;

Freeman, E ;

Grisso, JA ;

Rader, DJ ;

Sammel, M ;

Kapoor, S ;

Nestler, JE .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (11) :3896-3902

[3]

Barrett-Connor E, 1999, J REPROD MED, V44, P1012

[4] A prospective longitudinal study of serum testosterone, dehydroepiandrosterone sulfate, and sex hormone-binding globulin levels through the menopause transition [J].

Burger, HG ;

Dudley, EC ;

Cui, JS ;

Dennerstein, L ;

Hopper, JL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2000, 85 (08) :2832-2838

[5] REPLACEMENT OF DEHYDROEPIANDROSTERONE ENHANCES T-LYMPHOCYTE INSULIN BINDING IN POSTMENOPAUSAL WOMEN [J].

CASSON, PR ;

FAQUIN, LC ;

STENTZ, FB ;

STRAUGHN, AB ;

ANDERSEN, RN ;

ABRAHAM, GE ;

BUSTER, JE .

FERTILITY AND STERILITY, 1995, 63 (05) :1027-1031

[6] TESTOSTERONE ENHANCES ESTRADIOLS EFFECTS ON POSTMENOPAUSAL BONE-DENSITY AND SEXUALITY [J].

DAVIS, SR ;

MCCLOUD, P ;

STRAUSS, BJG ;

BURGER, H .

MATURITAS, 1995, 21 (03) :227-236

[7] METABOLISM OF DIHYDROTESTOSTERONE TO 5-ALPHA-ANDROSTANE-3-ALPHA,17-BETA-DIOL GLUCURONIDE IS GREATER IN THE PERIPHERAL COMPARTMENT THAN IN THE SPLANCHNIC COMPARTMENT [J].

DUFFY, DM ;

LEGRO, RS ;

CHANG, L ;

STANCZYK, FZ ;

LOBO, RA .

FERTILITY AND STERILITY, 1995, 64 (04) :736-739

[8] Addition of testosterone to estrogen replacement therapy in oophorectomized women:: effects on sexuality and well-being [J].

Flöter, A ;

Nathorst-Böös, J ;

Carlström, K ;

von Schoultz, B .

CLIMACTERIC, 2002, 5 (04) :357-365

[9] Administration of testosterone undecanoate in postmenopausal women:: Effects on androgens, estradiol, and gonadotrophins [J].

Flöter, A ;

Carlström, K ;

von Schoultz, B ;

Nathorst-Böös, J .

MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2000, 7 (04) :251-256

[10]

Greene RR, 1942, ENDOCRINOLOGY, V30, P734, DOI 10.1210/endo-30-5-734

← 1 2 3 →