Stereocontrolled synthesis of enantiopure substituted 4-aminopyrrolidin-2-ones

被引：31

作者：

Langlois, N

Calvez, O

Radom, MO

机构：

[1] Inst. Chim. Substances Naturelles, C.N.R.S.

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(97)10216-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The highly diastereoselective conjugate addition of N-benzylhydroxylamine and benzylamine to alpha,beta-unsaturated lactam 3 provided an efficient entry to enantiopure (4S,5S)-4-amino-5-hydroxymethylpyrrolidin-2-ones. (C) 1997 Elsevier Science Ltd.

引用

页码：8037 / 8040

页数：4

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