Human enzyme polymorphism in the Canary Islands .7. G6PD Seattle in Canarians and North African Berbers

被引：5

作者：

Cabrera, VM ^{[1
]}

Gonzalez, P ^{[1
]}

Salo, WL ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT BIOCHEM & MOLEC BIOL,DULUTH,MN 55812

来源：

HUMAN HEREDITY | 1996年 / 46卷 / 04期

关键词：

glucose-6-phosphate dehydrogenase; Seattle variant; Canarian; Berbers; DNA sequence;

D O I：

10.1159/000154353

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Sequence analysis of the glucose-6-phosphate dehydrogenase (G6PD) variant Cc, characterized by slower electrophoretic mobility than G6PD-B, in 14 Canarian and 2 Berber males, has revealed that all of them share the G --> C mutation at nucleotide 844 in exon 8 leading to an Asp --> His substitution at amino acid 282 known as G6PD Seattle. No additional differences have been detected among them nor with the common haplotype previously found for this variant.

引用

页码：197 / 200

页数：4

共 22 条

[1] ALFONSO JM, 1989, HUM BIOL, V61, P543
[2] [Anonymous], 1976, Handbook of enzyme electrophoresis in human genetics
[3] BEUTLER E, 1991, J BIOL CHEM, V266, P4145
[4] BREWER GJ, 1970, INTRO ISOZYME TECHNI
[5] CALABRO V, 1993, AM J HUM GENET, V52, P527
[6] DEVITA G, 1989, AM J HUM GENET, V44, P233
[7] GONZALEZ R, 1981, ABORIGENES CANARIOS
[8] SIMPLE PROCEDURE OF DNA ISOLATION FROM HUMAN SERUM
ISHIZAWA, M
KOBAYASHI, Y
MIYAMURA, T
MATSUURA, S
[J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (20) : 5792 - 5792
[9] KIRKMAN HN, 1965, J LAB CLIN MED, V66, P834
[10] Larruga J M, 1992, Gene Geogr, V6, P159

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