Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58

被引:492
作者
Goodner, B
Hinkle, G
Gattung, S
Miller, N
Blanchard, M
Qurollo, B
Goldman, BS
Cao, YW
Askenazi, M
Halling, C
Mullin, L
Houmiel, K
Gordon, J
Vaudin, M
Iartchouk, O
Epp, A
Liu, F
Wollam, C
Allinger, M
Doughty, D
Scott, C
Lappas, C
Markelz, B
Flanagan, C
Crowell, C
Gurson, J
Lomo, C
Sear, C
Strub, G
Cielo, C
Slater, S
机构
[1] Cereon Genom LLC, Cambridge, MA 02139 USA
[2] Univ Richmond, Dept Biol, Richmond, VA 23173 USA
[3] Hiram Coll, Dept Biol, Hiram, OH 44234 USA
[4] Monsanto Co, St Louis, MO 63167 USA
关键词
D O I
10.1126/science.1066803
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Agrobacterium tumefaciens is a plant pathogen capable of transferring a defined segment of DNA to a host plant, generating a gall tumor. Replacing the transferred tumor-inducing genes with exogenous DNA allows the introduction of any desired gene into the plant. Thus, A. tumefaciens has been critical for the development of modern plant genetics and agricultural biotechnology. Here we describe the genome of A. tumefaciens strain C58, which has an unusual structure consisting of one circular and one linear chromosome. We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants.
引用
收藏
页码:2323 / 2328
页数:6
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共 62 条
  • [1] PRESENCE OF ONE LINEAR AND ONE CIRCULAR CHROMOSOME IN THE AGROBACTERIUM-TUMEFACIENS C58 GENOME
    ALLARDETSERVENT, A
    MICHAUXCHARACHON, S
    JUMASBILAK, E
    KARAYAN, L
    RAMUZ, M
    [J]. JOURNAL OF BACTERIOLOGY, 1993, 175 (24) : 7869 - 7874
  • [2] The genome sequence of Rickettsia prowazekii and the origin of mitochondria
    Andersson, SGE
    Zomorodipour, A
    Andersson, JO
    Sicheritz-Pontén, T
    Alsmark, UCM
    Podowski, RM
    Näslund, AK
    Eriksson, AS
    Winkler, HH
    Kurland, CG
    [J]. NATURE, 1998, 396 (6707) : 133 - 140
  • [3] Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid
    Barnett, MJ
    Fisher, RF
    Jones, T
    Komp, C
    Abola, AP
    Barloy-Hubler, F
    Bowser, L
    Capela, D
    Galibert, F
    Gouzy, J
    Gurjal, M
    Hong, A
    Huizar, L
    Hyman, RW
    Kahn, D
    Kahn, ML
    Kalman, S
    Keating, DH
    Palm, C
    Peck, MC
    Surzycki, R
    Wells, DH
    Yeh, KC
    Davis, RW
    Federspiel, NA
    Long, SR
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (17) : 9883 - 9888
  • [4] The MutT proteins or ''nudix'' hydrolases, a family of versatile, widely distributed, ''housecleaning'' enzymes
    Bessman, MJ
    Frick, DN
    OHandley, SF
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (41) : 25059 - 25062
  • [5] Microbial degradation of tannins - A current perspective
    Bhat, TK
    Singh, B
    Sharma, OP
    [J]. BIODEGRADATION, 1998, 9 (05) : 343 - 357
  • [6] CELL BIOLOGY OF AGROBACTERIUM INFECTION AND TRANSFORMATION OF PLANTS
    BINNS, AN
    THOMASHOW, MF
    [J]. ANNUAL REVIEW OF MICROBIOLOGY, 1988, 42 : 575 - 606
  • [7] Brucellosis: a worldwide zoonosis
    Boschiroli, ML
    Foulongne, V
    O'Callaghan, D
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2001, 4 (01) : 58 - 64
  • [8] Conserved gene cluster at replication origins of the α-proteobacteria Caulobacter crescentus and Rickettsia prowazekii
    Brassinga, AKC
    Siam, R
    Marczynski, GT
    [J]. JOURNAL OF BACTERIOLOGY, 2001, 183 (05) : 1824 - 1829
  • [9] Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021
    Capela, D
    Barloy-Hubler, F
    Gouzy, J
    Bothe, G
    Ampe, F
    Batut, J
    Boistard, P
    Becker, A
    Boutry, M
    Cadieu, E
    Dréano, S
    Gloux, S
    Godrie, T
    Goffeau, A
    Kahn, D
    Kiss, E
    Lelaure, V
    Masuy, D
    Pohl, T
    Portetelle, D
    Pühler, A
    Purnelle, B
    Ramsperger, U
    Renard, C
    Thébault, P
    Vandenbol, M
    Weidner, S
    Galibert, F
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (17) : 9877 - 9882
  • [10] Telomeres of the linear chromosomes of Lyme disease spirochaetes: nucleotide sequence and possible exchange with linear plasmid telomeres
    Casjens, S
    Murphy, M
    DeLange, M
    Sampson, L
    vanVugt, R
    Huang, WM
    [J]. MOLECULAR MICROBIOLOGY, 1997, 26 (03) : 581 - 596