Wiring the zebrafish: axon guidance and synaptogenesis

被引:35
作者
Hutson, LD [1 ]
Chien, CB [1 ]
机构
[1] Univ Utah, Med Ctr, Dept Neurobiol & Anat, Salt Lake City, UT 84132 USA
关键词
D O I
10.1016/S0959-4388(02)00294-5
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.
引用
收藏
页码:87 / 92
页数:6
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