BCSH/BSBMT guideline: diagnosis and management of veno-occlusive disease (sinusoidal obstruction syndrome) following haematopoietic stem cell transplantation

被引：259

作者：

Dignan, Fiona L. ^{[1
]}

Wynn, Robert F. ^{[2
]}

Hadzic, Nedim ^{[3
,4
]}

Karani, John ^{[5
]}

Quaglia, Alberto ^{[6
]}

Pagliuca, Antonio ^{[7
]}

Veys, Paul ^{[8
]}

Potter, Michael N. ^{[9
]}

机构：

[1] Cent Manchester NHS Fdn Trust, Dept Haematol, Manchester, Lancs, England

[2] Royal Manchester Childrens Hosp, Manchester M27 1HA, Lancs, England

[3] Kings Coll Hosp London, Paediat Liver Serv, London, England

[4] Kings Coll Hosp London, Inst Liver Studies, London, England

[5] Kings Coll Hosp London, Dept Radiol, London, England

[6] Kings Coll Hosp London, Dept Histopathol, London, England

[7] Kings Coll Hosp London, Dept Haematol Med, London, England

[8] Great Ormond St Hosp Sick Children, Dept Bone Marrow Transplantat, London, England

[9] Royal Marsden NHS Fdn Trust, Sect Haematooncol, London, England

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2013年 / 163卷 / 04期

关键词：

veno-occlusive disease; prophylaxis; transplant; defibrotide; sinusoidal obstruction syndrome; BONE-MARROW-TRANSPLANTATION; TISSUE-PLASMINOGEN ACTIVATOR; REGIMEN-RELATED TOXICITIES; MOLECULAR-WEIGHT HEPARIN; MR-IMAGING FINDINGS; LOW-DOSE HEPARIN; HEPATIC COMPLICATIONS; URSODEOXYCHOLIC ACID; LIVER-TRANSPLANTATION; VENOCCLUSIVE DISEASE;

D O I：

10.1111/bjh.12558

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

A joint working group established by the Haemato-oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Blood and Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of veno-occlusive disease of the liver following haematopoietic stem cell transplantation (HSCT). This guideline includes recommendations for both prophylaxis and treatment of the condition and includes recommendations for children and adults undergoing HSCT.

引用

页码：444 / 457

页数：14

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