A new alkaloid and its artificial derivative with an indazole ring from Nigella glandulifera

被引：89

作者：

Liu, YM

Yang, JS

Liu, QH

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100094, Peoples R China

[2] Peking Univ, Coll Med, Beijing 100094, Peoples R China

[3] Xinjiang Inst Mat Med, Urumqi 830001, Peoples R China

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2004年 / 52卷 / 04期

关键词：

Nigella glandulifera; indazole alkaloid; zwitterion; nigeglanine;

D O I：

10.1248/cpb.52.454

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new compound, nigeglanine (1), and its new artificial derivative (la), were isolated from the seeds of Nigella glandulifera, together with a known aporphine alkaloid, fuzitine (2). Their structures were established by spectral analysis, including two-dimensional (2D)-NMR spectroscopy. Nigeglanine (1) is the third natural product determined to contain an indazole nucleus.

引用

页码：454 / 455

页数：2

共 5 条

[1] ISOLATION AND STRUCTURE DETERMINATION OF NIGELLICINE, A NOVEL ALKALOID FROM THE SEEDS OF NIGELLA-SATIVA [J].